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ED Pharmacy

Erectile Dysfunction treatment made simple

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Product Description

  • Contains the active ingredient, Avanafil
  • Fast-acting treatment for male Erectile Dysfunction
  • Only to be taken as and when required, 15-30 minutes before sexual activity
  • Not to be used with other erectile dysfunction treatments

Further Information

There are many causes for erectile dysfunction, including medical reasons, age, stress factors, lifestyle, inadequate rest, or smoking and alcohol. In some of these circumstances, patients can make some changes to combat these effects. In certain circumstances, lifestyle changes alone may be inadequate, and treatment using medicines may be considered. In all cases, reducing risk factors by making lifestyle modifications should accompany treatment using ED medication.

As the name suggests, Spedra is a fast-acting treatment to combat the effects of erectile dysfunction and can be taken as little as 15 minutes before sexual activity. It contains the active drug, Avanafil, which belongs to a family of medicines called phosphodiesterase type 5 (PDE) inhibitors. PDE inhibitors are medicines that prevent the phosphodiesterase enzyme from breaking down the messengers responsible for the relaxation of smooth muscle and therefore widening of blood vessels in the penis when stimulated. This dilation improves blood circulation and increases blood flow which therefore leads to a better erection.

This group of medication is commonly used to treat erectile dysfunction, and there are other different drugs within this group such as Sildenafil, Tadalafil, and Vardenafil. Although Avanafil is only licensed to treat ED, other drugs within this group can be used to treat conditions such as certain types of high blood pressure. It is therefore used with caution in patients with cardiovascular disease and severe heart failure or hypotension (low blood pressure).

There is no generic alternative for Spedra (Avanafil) as is the case for Viagra (Sildenafil), Cialis (Tadalafil) and Levitra (Vardenafil). Generic Avanafil should be available mid-2025, this should mean cheaper alternatives will be available from other manufacturers.



  • There are three strengths of Spedra currently available; 50mg, 100mg and 200mg tablets.
  • It is recommended that Spedra be taken on an empty stomach to achieve maximum efficacy. When taken with high-fat foods, the drug’s rate of absorption significantly decreases, which may delay the desired effect.
  • The effects of Spedra can last up to six hours.
  • Spedra should not be taken by anyone under the age of eighteen or by those who experience no trouble in achieving an erection.


Side Effects of using Spedra

As with all medications, Spedra can have unpleasant side effects even when taken correctly. The most common of these are:

  • Headaches
  • Nasal complaints
  • Vasodilation

These side effects are not cause for great concern and should last only a short time.

However, if you experience a painful erection that will not go down, contact your nearest medical centre or out-of-hours service for help.

To determine if Spedra is a suitable treatment for you, please select your preferred option and proceed to the assessment page.

Spedra is licensed for erectile dysfunction and comes as an orally administered tablet in the following three strengths:

50 mg
100 mg
200 mg

When taken orally, Spedra may begin to work in as little as 15 minutes.

Directions: Take one tablet when required 15-30 minutes prior to sexual activity

How long will it take Spedra to work?

As the name suggests, Spedra is one the fastest-acting ED treatments and can begin to work in as little as 15 minutes after oral administration. We recommend taking one tablet 15-30 minutes prior to sexual activity.

What does Spedra look like?

Spedra is usually a pale yellow oval-shaped tablet

How long will the effects of Spedra last?

The effects should last a minimum of four hours and a maximum of up to six hours.

Can Spedra be used alongside other erectile dysfunction medication?

No, they cannot. All medications that treat erectile dysfunction work the same way and so using multiple forms at one time can cause an overdose and a higher chance of serious side effects. Combinations of ED treatment should not be taken without a 36-hour break between one medicine and another

Is there a generic version of Spedra?

No, at the moment Avanafil is only available in the brand, Spedra. Generic variations should be available mid-2025.

Is Spedra legal to purchase online in the UK?

Yes, Spedra can be purchased online in the UK from GPhC-approved websites. As we are regulated and approved by the GPhC you can be confident with the request. One of our prescribers will issue a prescription (free of charge) to our in-house pharmacy if deemed suitable.

Can I drink grapefruit juice with Spedra?

No, you must not drink grapefruit juice at the same time as it increases exposure to the drug. If you drink grapefruit you must avoid doing so at least 24 hours before administering Spedra

Can I drink alcohol with Spedra?

Alcohol and Spedra can increase the chances of hypotension (low blood pressure) while increasing your heart rate. It can cause excessive dizziness and fainting. Alcohol is also a contributing factor to erectile dysfunction

Is Spedra fine to take if I am on other medication?

There are certain medicines that can interact with Spedra. It is important to answer all questions accurately, honestly, and thoroughly to allow us to assess your suitability for treatment. Not all medicines are safe to take with Spedra and sometimes an adjustment in dose is required.

Can I drive after taking Spedra?

Side effects of using sildenafil may include blurred vision and dizziness so you should refrain from driving or operating machinery until you know that the drug does not affect you in any of these ways.

Chris Morphe

Chris Morphe

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